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The first PICOSALAX sachet is taken the night before the procedure, and the second is taken the next day, in the morning prior to the procedure.
On the day before the procedure - 1 sachet: The first reconstituted sachet is taken in the evening (e.g. 5:00 to 9:00 pm), followed by at least five 250mL drinks of clear liquids, spread over several hours
On the day of the procedure - 1 sachet: The second reconstituted sachet is taken in the morning (5-9 hours before the procedure), followed by at least three 250mL drinks of clear liquids, spread over several hours Clear liquids may be consumed until 2 hours before the time of the procedure.